Table I.
Author | Year | Country | Number of patients | Duration of follow-up [months] | Treatment | Antibody type | Detection method | Cut-off value | Study quality | OS | DFS | ||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HR | 95% CI | HR | 95% CI | ||||||||||
Jiang et al. | 2016 | China | 90 | 80 | Hepatectomy | Goat monoclonal | IHC | 25% | 8 | 1.7 | 1.06–2.95 | NA | NA |
Chen et al. | 2013 | China | 193 | 51 | Hepatectomy | Monoclonal | IHC | Score > 150 | 6 | 1.696 | 1.16 – 2.479 | 1.765 | 1.1–2.026 |
Ye et al. | 2016 | China | 284 | 60 | Hepatectomy | Monoclonal | IHC | Score > 2 | 7 | 1.846 | 1.281–2.660 | 1.772 | 1.039–3.023 |
Bao et al. | 2013 | China | 75 | 20 | Hepatectomy | Rabbit monoclonal | IHC | 20% | 6 | 3.7 | 1.8–7.61 | NA | NA |
Sun et al. | 2011 | China | 36 | 18.5 | Hepatectomy | Goat monoclonal | IHC | NA | 6 | 1.11 | 0.23–5.26 | NA | NA |
Shan et al. | 2013 | China | 60 | 36 | Hepatectomy | Goat monoclonal | IHC | NA | 5 | 0.338 | 0.132–0.855 | 0.485 | 0.242–0.972 |
Sai et al. | 2015 | China | 157 | 60 | Hepatectomy | Monoclonal | IHC | 25% | 7 | 1.66 | 1.09–2.53 | NA | NA |
Dai et al. | 2015 | China | 217 | 84 | Hepatectomy | NA | IHC | NA | 7 | 2.51 | 1.45–4.34 | NA | NA |
Li et al. | 2015 | China | 180 | 36 | Hepatectomy | NA | IHC | 25% | 6 | 2.01 | 1.26–3.22 | NA | NA |
OS – overall survival, DFS – disease-free survival, NA – not available, IHC – immunohistochemistry, CI – confidence interval, HR – hazard ratio.