Table II.
Parameter | HLP3 n = 2,239 (1.74%) | No HLP3 n = 126,246 (98.26%) | P-value |
---|---|---|---|
Age, % (n): | < 0.001 | ||
18–39 | 11.7 (262) | 15.4 (19,347) | |
40–75 | 76.2 (1,700) | 73.6 (92,689) | |
> 75 | 12.1 (270) | 11.0 (13,923) | |
Sex, % (n): | < 0.001 | ||
Male | 27.9 (622) | 45.1 (56,590) | |
Female | 72.1 (1,606) | 54.9 (68,986) | |
Presence of diabetes, % (n) | 17.8 (399) | 20.2 (25,490) | 0.006 |
Presence of hypertension, % (n) | 25.3 (567) | 25.6 (32,256) | 0.808 |
Total cholesterol, median (IQR) | 206 (177–239) | 197 (168–228) | < 0.001 |
ApoB, median (IQR) | 79 (66–93) | 92 (77–109) | < 0.001 |
HDL-C, median (IQR) | 67 (56–78) | 52 (42–64) | < 0.001 |
VLDL-C, median (IQR) | 30 (26–40) | 22 (17–29) | < 0.001 |
VLDL3-C, median (IQR) | 16 (14–22) | 13 (10–16) | < 0.001 |
RLP-C, median (IQR) | 34 (27–46) | 26 (20–34) | < 0.001 |
IDL-C, median (IQR) | 17 (13–25) | 13 (9–19) | < 0.001 |
Estimated LDL-C, median (IQR) | 107 (85–134) | 117 (94–144) | < 0.001 |
LDL-Cr, median (IQR) | 73 (48–99) | 95 (73–119) | < 0.001 |
TG, median (IQR) | 161 (144–196) | 109 (78–157) | < 0.001 |
ApoB – apolipoprotein B, estimated LDL-C – low-density lipoprotein cholesterol via Martin/Hopkins equation estimation, HDL-C – high-density lipoprotein cholesterol, HLP3 – type III familial hyperlipoproteinemias, IQR – interquartile range, LDL-Cr – real low-density cholesterol, RLP-C – remnant lipoprotein cholesterol, TG – triglyceride, VLDL-C – very-low density lipoprotein cholesterol, VLDL3-C – very-low density cholesterol subfraction 3.