Table III.

miRNAs differentially expressed in LC and HCC

miRNA	Tissue sample	Median or mean	P-value	Function related	Detected expression	Reference
hsa-miR-206	LC	0.02369	0.0313	Cell proliferation suppression, apoptosis	Low	[35, 36]
hsa-miR-637	LC and HCC	0.01019 and 0.006758	0.0156 and < 0.0001	LIF gene inhibition, induced STAT3 phosphorylation	Low	[33]
hsa-miR-15b	HCC	0.03091	0.0010	Apoptosis, proliferation, survival and angiogenesis	Low	[37, 38]
hsa-miR-125b	HCC	0.01632	0.0010	Cell invasion, tumour metastasis, VEGF regulation	Low	[37, 42]
hsa-miR-423-3p	HCC	0.02558	0.0010	Cell proliferation, cell cycle	Low	[46, 48]
hsa-miR-424	HCC	0.004519	0.0313	Angiogenesis regulation and cell invasion	Low	[51, 53]
hsa-miR-494	HCC	0.006319	< 0.0001	Cell cycle, sorafenib resistance, PTEN regulation	Low	[59]
hsa-miR-497	HCC	0.04621	< 0.0001	Invasion, proliferation, cell growth and apoptosis	Low	[63–66]
hsa-miR-612	HCC	0.00605	0.0078	Metastasis suppressor	Low	[69]
hsa-miR-1255b	HCC	0.00568	0.0156	No functional study in the literature	Low	–