TABLE 1.
Baseline participant characteristics
| Variables | Combined (n = 40) | Xylitol (n = 14) | Saline (n = 14) | Control (n = 12) | P value |
|---|---|---|---|---|---|
| Age in years, mean (SD) | 53.8 (7.8) | 53.7 (9.2) | 52.7 (6.7) | 55.0 (7.7) | .766 |
| Gender‐male, % (n) | 80.0 (32) | 71.4 (10) | 92.9 (13) | 75.0 (9) | .320 |
| Race/Ethnicity, % (n) | |||||
| Non‐Hispanic White | 77.5 (31) | 85.7 (12) | 57.1 (8) | 91.7 (11) | .072 |
| White Hispanic | 10.0 (4) | 7.1 (1) | 14.3 (2) | 8.3 (1) | |
| African American | 5.0 (2) | 7.1 (1) | 7.1 (1) | 0 | |
| Asian | 2.5 (1) | 0 | 7.1 (1) | 0 | |
| Pacific Islander/Hawaiian | 2.5 (1) | 0 | 7.1 (1) | 0 | |
| Multiple races | 2.5 (1) | 0 | 7.1 (1) | 0 | |
| Education, % (n) | |||||
| HS or less | 7.5 (3) | 7.1 (1) | 7.1 (1) | 8.3 (1) | .740 |
| Some college | 50.0 (20) | 57.1 (8) | 57.1 (8) | 33.3 (4) | |
| College graduate | 42.5 (17) | 35.7 (5) | 35.7 (5) | 58.3 (7) | |
| SNOT‐20 (SD) | 48.5 (12.7) | 50.8 (14.7) | 47.6 (13.7) | 47.2 (8.7) | .727 |
| SF‐36 (SD) | 57.3 (16.3) | 51.1 (15.8) | 59.0 (17.6) | 62.7 (14.1) | .177 |
| MFI (SD) | 60.4 (5.3) | 59.4 (5.4) | 60.5 (6.0) | 61.7 (4.7) | .578 |
| Sinusitis symptoms, years (SD) | 19.8 (7.7) | 20.5 (7.8) | 16.4 (9.9) | 22.4 (2.3) | .264 |
| Fatigue, years (SD) | 20.7 (6.6) | 19.3 (8.4) | 19.9 (6.0) | 23.8 (3.1) | .313 |
| CT | 3.9 (4.1) | 5.2 (4.4) | 3.7 (4.5) | 2.6 (3.1) | .274 |
| Endoscopy | 3.3 (1.9) | 3.1 (1.9) | 3.7 (1.8) | 3.1 (2.0) | .597 |
| Sleep | 42.9 (7.1) | 42.2 (5.6) | 44.7 (8.5) | 41.5 (7.0) | .473 |
| Wheeze | 21.5 (4.1) | 21.3 (4.4) | 21.6 (4.8) | 21.6 (3.3) | .975 |
| Tobacco use, % (n) | |||||
| Never | 40.0 (16) | 42.9 (6) | 42.9 (6) | 33.3 (4) | .323 |
| Current | 2.5 (1) | 0 | 0 | 1 (8.3) | |
| Past | 25.0 (8) | 35.7 (5) | 14.3 (2) | 8.3 (1) | |
Abbreviations: CT, computed tomography (0‐24 points); HS, high school; MFI, multidimensional fatigue index (0‐100 points); SF‐36, Short‐Form 36 (0‐100 points); SNOT‐20, sino‐nasal outcomes test‐20 (0‐100 points).