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. 2020 Mar 25;123(5):1657–1670. doi: 10.1152/jn.00701.2019

Fig. 2.

Fig. 2.

Effects of N-methyl-d-aspartate (NMDA) on the firing properties of the bursting neurons following chronic spinal transection. A: representative recording traces showing the effect of NMDA (bottom) on a bursting neuron, compared with that in control (top), on dorsal root stimulation (0.2 ms; arrow). B–G: group data showing the effects of NMDA on the firing properties (mean marked by X) of the bursting neurons in response to increasing stimulus intensity, compared with those during control and washout conditions. B: evoked spike count during control (n = 20 for all intensities), NMDA (n = 21; except n = 23 at 10×), and washout (n = 18 for all intensities) conditions. C: field potential during control (n = 20 for all intensities), NMDA (n = 21; except n = 23 at 10×), and washout (n = 18 for all intensities) conditions. D: field latency (only nonzero values) during control (n = 20 for all intensities), NMDA (n = 21; except n = 23 at 10×), and washout (n = 18 for all intensities) conditions. E: burst duration during control (n = 20 for all intensities), NMDA (n = 21; except n = 23 at 10×), and washout (n = 18 for all intensities) conditions. F: first-spike latency (only nonzero values) during control (n = 20; except n = 19 at 1×), NMDA (n = 18, 1×; n = 19, 2×; n = 21, 5×; n = 23, 10×), and washout (n = 16, 1×; n = 15, 2×; n = 18, 5× and 10×) conditions. G: spontaneous firing rate during control (n = 20 for all intensities), NMDA (n = 21; except n = 23 at 10×), and washout (n = 18 for all intensities) conditions. Significant difference from control (*P < 0.017) and washout (†P < 0.017) conditions using a post hoc pairwise comparison (t test) of group means with the Bonferroni correction is shown. The box and whisker plots show the minimum, first quartile, median, third quartile, and maximum, without outliers.