Table 4.
Common and Important Toxicities by CTC Grade and Body System
| Body System | CTC Name | G1 | G2 | G3 | G4 | G5 |
|---|---|---|---|---|---|---|
| Blood/bone marrow | Hemoglobin | 14 | 16 | 2 | 0 | 0 |
| Leukocytes | 6 | 5 | 6 | 4 | 0 | |
| Lymphopenia | 10 | 4 | 12 | 0 | 0 | |
| Constitutional symptoms | Fatigue | 47 | 17 | 3 | 0 | 0 |
| Cardiac general | Hypertension | 2 | 2 | 8 | 0 | 0 |
| Gastrointestinal | Anorexia | 34 | 5 | 1 | 0 | 0 |
| Diarrhea | 20 | 4 | 1 | 0 | 0 | |
| Mucositis | 46 | 15 | 2 | 0 | 0 | |
| Nausea | 31 | 4 | 0 | 0 | 0 | |
| Hemorrhage/bleeding | Hemorrhage (all sites) | 18 | 1 | 1 | 0 | 0 |
| Infection | Febrile neutropenia | 0 | 0 | 11 | 2 | 1 |
| Pneumonia | 0 | 0 | 3 | 0 | 1 | |
| Pulmonary embolism | 0 | 0 | 1 | 0 | 0 | |
| Metabolic/laboratory | Hyperglycemia | 9 | 4 | 0 | 0 | 0 |
| Hypertriglyceridemia | 15 | 2 | 0 | 0 | 0 | |
| Proteinuria | 3 | 10 | 0 | 0 | 0 | |
| Neurology | Neuropathy-sensory | 29 | 1 | 0 | 0 | 0 |
| Pulmonary/upper respiratory | Pneumonitis/pulmonary infiltrates | 1 | 0 | 2 | 0 | 0 |
| Vascular | Embolism | 0 | 1 | 0 | 0 | 0 |
| Thrombosis | 0 | 2 | 1 | 0 | 0 |
Abbreviations: CTC = common toxicity criteria; G = grade.