Table 1.
Demographics and tumour subtype representation in the UKCCMP COVID-19 cohort compared with the ONS cancer control population
| UKCCMP cohort (n=1044) | ONS cohort (n=282 878) | Odds ratio (95% CI) | p value | ||
|---|---|---|---|---|---|
| Sex | .. | .. | 1·26 (1·12–1·43) | 0·0002 | |
| Male | 595 (56·9%) | 145 034 (51·3%) | .. | .. | |
| Female | 445 (42·6%) | 137 844 (48·7%) | .. | .. | |
| Other | 4 (0·4%) | 0 | .. | .. | |
| Age, years | 70 (60–77) | NA* | .. | .. | |
| Cancer subtype (ICD-10 code) | |||||
| Breast (C50) | 143 (13·7%) | 46 109 (16·3%) | 0·82 (0·68–0·98) | 0·026 | |
| Colorectal (C18–C21) | 124 (11·9%) | 36 039 (12·7%) | 0·93 (0·76–1·12) | 0·46 | |
| Prostate (C61) | 114 (10·9%) | 41 200 (14·6%) | 0·72 (0·59–0·88) | 0·0008 | |
| Lung (C34) | 111 (10·6%) | 38 878 (13·7%) | 0·75 (0·61–0·91) | 0·0033 | |
| Digestive organs (non–colorectal) (C15–C17, C22–C26) | 95 (9·1%) | 30 096 (10·6%) | 0·84 (0·68–1·04) | 0·12 | |
| Urinary tract (C64–C68) | 77 (7·4%) | 19 333 (6·8%) | 1·09 (0·85–1·38) | 0·46 | |
| Female genital organs (C51–C58) | 56 (5·4%) | 17 969 (6·4%) | 0·84 (0·63–1·10) | 0·23 | |
| Lip, oral cavity, and pharynx (C00–C14) | 33 (3·2%) | 7558 (2·7%) | 1·19 (0·82–1·69) | 0·33 | |
| CNS (C69–C72) | 25 (2·4%) | 5038 (1·8%) | 1·36 (0·87–2·02) | 0·13 | |
| Mesothelial and soft tissue (C45–C49) | 16 (1·5%) | 4682 (1·7%) | 0·93 (0·53–1·52) | 0·90 | |
| Respiratory and intrathoracic organs (not lung; C30–C39) | 11 (1·1%) | 2780 (1·0%) | 1·08 (0·53–1·94) | 0·75 | |
| Bone and articular cartilage (C40–C41) | 4 (0·4%) | 376 (0·1%) | 2·90 (0·78–7·50) | 0·053 | |
| Male genital organs (C60–C63) | 4 (0·4%) | 2435 (0·9%) | 0·44 (0·12–1·14) | 0·13 | |
| Endocrine glands (C73–C75) | 4 (0·4%) | 3374 (1·2%) | 0·32 (0·09–0·82) | 0·0096 | |
| Lymphoma (C81–C85) | 79 (7·6%) | 13 537 (4·8%) | 1·63 (1·28–2·06) | <0·0001 | |
| Leukaemia (C91–C95) | 79 (7·6%) | 8018 (2·8%) | 2·82 (2·21–3·55) | <0·0001 | |
| Myeloma (C90) | 37 (3·5%) | 5033 (1·8%) | 2·03 (1·42–2·83) | 0·0001 | |
| Other haematological (C86, C88, C96) | 29 (2·8%) | 423 (0·1%) | 19·14 (12·59–28·05) | <0·0001 | |
Data are n (%) or median (IQR). Univariable analysis was done. p values were determined by Fisher's exact test and unadjusted for age and sex. NA=not available. ONS=Office for National Statistics. UKCCMP=UK Coronavirus Cancer Monitoring Project. ICD-10=International Classification of Diseases, 10th Revision.
*
Individual ages not available in the ONS dataset.