Table 1.
Baseline characteristics for patients in the pharmacogenetic analyses
| Parameters | Discovery (n = 1,188) | Confirmatory (n = 1,002) | Total (n = 2,190) |
|---|---|---|---|
| Age, median (range), y | 59 (18-86) | 56 (18-86) | 58 (18-86) |
| Sex, n (%) | |||
| Male | 557 (47) | 359 (36) | 916 (42) |
| Female | 631 (53) | 643 (64) | 1,274 (58) |
| Race, n (%) | |||
| White | 844 (71) | 811 (81) | 1,655 (76) |
| Asian | 325 (27) | 114 (11) | 439 (20) |
| Othera | 19 (2) | 77 (8) | 96 (4) |
| Baseline liver metastasis,b n (%) | |||
| Yes | 165 (14) | 208 (21) | 373 (17) |
| Baseline ALT, ×ULN | |||
| Median (range) | 0.46 (0.07-2.82) | 0.48 (0.06-6.91) | 0.47 (0.06-6.91) |
a
Includes 9 individuals with “unknown” race.
b
Baseline liver lesion data not available for VEG109603, VEG109599, VEG110190, and VEG102857.