FIGURE 5.

Human amniotic mesenchymal stromal cells (hAMSCs) reduce the presence of lymphoid aggregates in lung tissues of bleomycin‐challenged mice. Lymphoid aggregates (indicated with black arrows) were present in the lungs of bleomycin‐challenged mice. They were located in peri‐bronchial areas as shown in lung sections stained with hematoxylin and eosin (A,B). Immunofluorescence double staining for CD3 (T cells, green) and B220 (B cells, red) indicated that lung lymphoid aggregates are composed of T and B lymphocytes mixed in variable proportions (C‐F). Here, examples of aggregates with low (C,D), intermediate (E), and large (F) presence of B cells are reported. Scale bars = 100 μm (A,B); 50 μm (C‐F)