TABLE 2.
Baseline pulmonary function tests and emphysematous changes in the three study groups
| Slowed ageing n=353 | Normal ageing n=322 | Accelerated ageing n=99 | p-value | |
| Variable | ||||
| FVC % pred | 97±15 | 93±15 | 89±17 | <0.0001 |
| FEV1 % pred | 102±16 | 98±17 | 93±19 | <0.0001 |
| DLCO adjusted | 99±18 | 99±19 | 91±24 | 0.02 |
| DLCO/VA | 106±19 | 108±21 | 101±22 | 0.03 |
| 6MWT m | 455±122 | 454±114 | 396±152 | 0.0001 |
| O2 saturation at rest | 94.3±2.1 | 94.3±1.9 | 93.9±2.1 | <0.05 |
| Emphysema | 13 (4%) | 26 (8%) | 8 (9%) | <0.0001 |
Data are presented as mean±sd or n (%), unless otherwise stated. FVC: forced vital capacity; % pred: % predicted; FEV1: forced expiratory volume in 1 s; DLCO: diffusing capacity carbon monoxide; VA: alveolar volume; 6MWT: 6-min walking test.