Table 3.

Association between Rab27 expression and clinicopathological characteristics.

Characteristic	Number of studies	Number of patients	Pooled OR (95% CI)	p value	Heterogeneity
					I2 (%)	p value	Model
Age (old vs young)
Rab27A	4	579	1.23 (0.86–1.77)	0.255	0.0	0.820	Fixed
Rab27B	7	984	1.11 (0.84–1.48)	0.450	32.4	0.181	Fixed
Gender (male vs female)
Rab27A	4	579	0.69 (0.47–1.01)	0.057	33.9	0.209	Fixed
Rab27B	5	660	0.88 (0.43–1.82)	0.729	74.2	0.004	Random
Tumor size (large vs small)
Rab27B	3	414	1.17 (0.77–1.79)	0.454	0.0	0.386	Fixed
Tumor grade (high vs low)
Rab27A	3	446	1.20 (0.29–5.03)	0.800	82.8	0.003	Random
Rab27B	6	851	1.33 (0.75–2.35)	0.333	55.8	0.046	Random
Tumor stage (high vs low)
Rab27A	3	431	1.02 (0.37–2.78)	0.974	81.3	0.005	Random
Rab27B	5	723	1.43 (1.80–2.57)	0.229	61.3	0.036	Random
Lymph node metastasis (present vs absent)
Rab27A	3	431	1.53 (1.00–2.34)	0.048	49.6	0.137	Fixed
Rab27B	6	836	2.15 (1.56–2.95)	< 0.001	27.9	0.225	Fixed
Distant metastasis (present vs absent)
Rab27A	2	298	2.13 (0.10–44.08)	0.624	78.5	0.031	Random
Rab27B	3	422	6.80 (3.12–14.85)	< 0.001	0.0	0.982	Fixed
TNM stage (high vs low)
Rab27A	4	579	1.78 (0.79–4.02)	0.167	72.9	0.011	Random
Rab27B	6	881	2.55 (1.78–3.65)	< 0.001	30.9	0.204	Fixed

CI confidential interval, OR odds ratio, TNM tumor-node-metastasis.