Table 4.

Characteristics of RELB, NFKB2, pSTAT3 and CA9 IHC expression in the meningioma cohort.

Gene	Number (%)	Univariate analysis for RFS (Cox regression)			Multivariate analysis for RFS*			Association with PD-L1 expression
		p	HR	CI (95%)	p	HR	CI (95%)	ANOVA test (p)
RELB	91 (100)	0.14	1.69	0.83–3.43				0.8
Low	67 (74)		1.27	0.79–2.04
High	24 (26)
NFKB2	88 (100)	0.0004	3.14	1.60–6.14	0.06	2.05	0.96–4.39	0.02
Low	62 (70)
High	26 (30)
WHO grade					0.04	1.85	1.03–3.30
Extent of resection					0.01	2.67	1.24–5.75
pSTAT3	73 (100)	0.13	1.81	0.83–3.97				0.14
Low	27 (37)
High	46 (63)
CA9	72 (100)	0.02	2.4	1.13–5.09	0.03	2.39	1.09–5.24	0.02**
Negative	35 (49%)
Positive	37 (51%)
WHO grade					0.07	1.72	0.95–3.14
Extent of resection					0.01	2.74	1.23–6.13

*Multivariate analysis for WHO grade, extent of resection (GTR/STR).

**Primary meningioma.