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. 2020 Aug 24;10:14145. doi: 10.1038/s41598-020-71062-2

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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FAM83H-AS1 knockdown impairs cellular migration and induces cell death in breast cancer cells. (A) Transwell in vitro migration assays in MCF7 cells. (B) Caspase 3 activity assays in MCF7 cells. (C) Heatmap of the 3 gene sets enriched in the high FAM83H-AS1 expression group (blue) compared with that of FAM83H-AS1 low expression samples (green). (D) Constellation Map of the 3 gene sets. Three connected clusters of gene sets (migration, apoptosis and cell death and necrosis pathways) are detected in the low-FAM83H-AS1 group.