Table 2.
Examples of differentially expressed genes in the FAM83H-AS1 high versus. low BRCA sample.
| Description | Pathway | Fold change (log2) | padj-value |
|---|---|---|---|
| Myosin Light chain 2 | Tight junction signaling | 4.268825581 | 3.38E−52 |
| Myosin heavy chain 2 | WNT signaling pathway | 3.267559072 | 9.51E−42 |
| Actin alpha 1 | WNT signaling pathway | 2.247491528 | 1.06E−30 |
| Leptin | Cell migration | − 2.03868572 | 1.10E−08 |
| MicroRNA 181 | Cell migration | − 1.757287497 | 8.07E−06 |
| Nuclear receptor 1 H4 | Cell migration | − 1.923864676 | 1.47E−05 |
| Fibroblast Growth Factor 4 | MAPK signaling/Focal adhesion | − 1.60587355 | 9.78E−08 |
| Fibroblast Growth Factor 21 | MAPK signaling/Focal adhesion | − 1.813231804 | 3.74E−05 |
| Claudin 17 | Epithelial to mesenchymal transition | − 1.609953043 | 0.00048284 |
| Insulin like growth factor binding protein 1 | PI3K pathway | − 3.010911164 | 1.75E−11 |
| Cadherin 9 | Cadherin signaling | − 1.579133916 | 2.44E−05 |
| Hydroxy-delta-5-steroid dehydrogenase | Steroid synthesis | − 1.961005522 | 1.57E−10 |
| UDP glucuronosyltransferase family 1 member A1 | Steroid synthesis | − 1.554304254 | 0.001164245 |
| Alcohol dehydrogenase 1A (class I) alpha polypeptide | Drug metabolism | − 2.556929166 | 4.05E−09 |
| Cytochrome P450 family 2 subfamily A member 6 | Drug metabolism | − 2.989324666 | 3.13E−09 |
| Deathassociated protein kinase 3 | Cell death regulation | − 0.277 | 1.15E−04 |
| Tumor protein p53 | Cell death regulation | 0.139 | 5.00E−02 |
| TNF receptor superfamily member 11b | Cell death regulation | − 0.126 | 4.22E − 01 |
| BCL2 associated X, apoptosis regulator | Apoptosis regulation | − 0.136 | 6.64E−02 |
| BH3-like motif containing cell death inducer | Cell death regulation | − 2.779 | 1.07E−11 |
| Phosphate and tensin homolog | Cell survival signaling | − 0.19 | 1.46E−03 |