Table 3.
Examples of differentially expressed genes after FAM83H-AS1 knockdown in MCF7 cells.
| Gene symbol | Description | Pathway | Fold change (sh-FAM83H-AS1 vs. sh-RANDOM) | p value |
|---|---|---|---|---|
| CLDN1 | Claudin 1 | Epithelial to mesenchymal transition | 1.64 | 0.023413 |
| TP63 | Tumor protein p63 | Apoptosis signaling | 1.56 | 0.017146 |
| H3F3C | H3 histone, family 3C | DNA replication | 1.51 | 0.033872 |
| FGF18 | Fibroblast growth factor 18 | MAPK signaling/Focal adhesion | − 1.43 | 0.000613 |
| DDX60 | DEAD (Asp–Glu–Ala–Asp) box polypeptide 60 | Cell death regulation | − 1.45 | 0.008851 |
| IFI6 | Interferon, alpha-inducible protein 6 | Interferon signaling | − 2.4 | 0.003207 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | Cell death regulation | − 1.54 | 0.018695 |
| GPER1 | G-protein coupled estrogen receptor 1 | Endocrine resistance | − 1.31 | 0.0286 |
| PARP9 | Poly(ADP-ribose) polymerase family member 9 | DNA repair | − 1.34 | 0.001424 |
| GSTM3 | Glutathione S + S transferase mu 3 (brain) | Drug metabolism | − 1.49 | 0.012426 |