Table 4.

Association Between SIX6 (rs33912345) and Peripapillary Retinal Nerve Fiber Thickness Parameters From Combined Analyses of Three Etnic Groups

	Global RNFL		Superior Quandrant		Inferior Quandrant
	β*	P Value	β*	P Value	β*	P Value
Model 1†	−0.882	4.9E-4	−1.216	2.6E-3	−1.712	5.7E-5
Model 2‡	−0.847	8.8E-4	−1.172	4.0E-3	−1.682	8.4E-5

^*Changes in RNFL thickness (in µm) per risk allele C of rs33912345.

^†Model 1 adjusted for age, gender, top three genotype PCs, and disc area.

^‡Model 2 adjusted for age, gender, top three genotype PCs, disc area, rs1900004 (ATOH7 gene), rs1360589 (CDKN2B-AS1), rs1192415 (TGFBR3-CDC7).