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. 2020 Jun 29;53(8):e12867. doi: 10.1111/cpr.12867

FIGURE 3.

FIGURE 3

The anti‐tumour effect of propofol by downregulation of miRNAs or lncRNAs in cancer cells. AKT, protein kinase B; ATG5, autophagy‐related genes 5; HOTAIR, HOX antisense intergenic RNA; HOXA11‐AS, HOXA11 Antisense RNA; MALAT1, metastasis‐associated lung adenocarcinoma transcript 1; miR, microRNAs; mTOR, mammalian target of rapamycin; p27, cyclin‐dependent kinase inhibitor 1B; PI3K, phosphoinositide 3‐kinase; RAC1, Ras‐related C3 botulinum toxin substrate 1; Wnt, wingless and proto‐oncogene integration‐1. “Arrows from propofol to → targets” means “activating targets.” “Blockade from propofol to targets” means “inhibiting targets”