Figure 2.

Significant brain clusters associated with attention-deficit/hyperactivity disorder (ADHD) symptoms and dyssomnia in the Adolescent Brain Cognitive Development Study at baseline. Multiple comparison correction includes voxel-level p < .001 and cluster-level familywise error correction p < .05 for ADHD and p < .025 for dyssomnia estimated by a multilevel block permutation accounting for family relatedness. The color bar represents t value. Age, sex, handedness, race, puberty, body mass index, site, household income, parental education, head motion, and total intracranial volume were controlled for in all analyses. (A) Brain regions significantly associated with ADHD symptoms. (B) Brain regions significantly associated with dyssomnia. (C) Brain regions significantly associated with ADHD or dyssomnia. Red areas are associated with ADHD, blue areas are associated with dyssomnia, and purple areas are the overlapping regions. L, left; R, right.