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. 2020 Aug 20;13:8299–8311. doi: 10.2147/OTT.S257729

Table 1.

Significant Changes in IQGAP Expression at the Transcriptional Level Between Different Types of CRC Tissues and Normal Tissues (ONCOMINE Database)

Gene Cancer vs Normal Data Set Fold Change P value t-test Ref.
IQGAP1 N/A N/A N/A N/A N/A
IQGAP2 Colon Adenocarcinoma vs Normal Kaiser Colon Statistics −3.25 2.23E-16 −12.60 [57]
Cecum Adenocarcinoma vs Normal Kaiser Colon Statistics −2.656 1.59E-7 −7.826
Colon Mucinous Adenocarcinoma vs Normal Kaiser Colon Statistics −2.133 4.11E-7 −8.086
Rectosigmoid Adenocarcinoma vs Normal Kaiser Colon Statistics −2.932 2.89E-5 −6.7210
Colon Adenocarcinoma vs Normal Ki Colon Statistics −2.829 2.11E-5 −8.995 [58]
Colorectal Carcinoma vs Normal Hong Colorectal Statistics −5.396 7.18E-23 −14.578 [35]
Rectal Adenocarcinoma vs Normal Gaedcke Colorectal Statistics −3.874 1.23E-36 −19.888 [59]
Colon Adenocarcinoma vs Normal TCGA Colorectal Statistics −3.528 1.16E-24 −14.525 [36]
Rectosigmoid Adenocarcinoma vs Normal TCGA Colorectal Statistics −5.547 2.49E-9 −16.820
Rectal Adenocarcinoma vs Normal TCGA Colorectal Statistics −3.584 1.09E-19 −11.947
Colon Adenoma Epithelia vs Normal Skrzypczak Colorectal 2 Statistics −4.411 1.42E-7 −22.666 [60]
Colon Carcinoma vs Normal Skrzypczak Colorectal 2 Statistics −2.739 5.43E-8 −12.184
Colon Carcinoma Epithelia vs Normal Skrzypczak Colorectal 2 Statistics −2.192 5.28E-8 −15.691
Colon Adenoma vs Normal Skrzypczak Colorectal 2 Statistics −5.899 3.74E-6 −13.834
Colorectal Carcinoma vs Normal Skrzypczak Colorectal Statistics −2.847 1.38E-11 −8.36 [60]
IQGAP3 Rectal Mucinous Adenocarcinoma vs Normal TCGA Colorectal Statistics 2.384 7.72E-6 6.864 [36]
Colorectal Carcinoma vs Normal Hong Colorectal Statistics 2.581 1.72E-7 5.834 [35]