Table 3.
Gene expression levels of 19 selected genes, which were differently expressed between obese and non-obese rats, in obese (n = 30) and non-obese (n = 20) adults
| Gene name | Obese (n = 30) (means ± SD) | Non-obese (n = 20) (means ± SD) | p value |
|---|---|---|---|
| TFEC | 0.41±0.36 | 0.75±0.47 | 0.0052 |
| CCL2 | 13.99±9.98 | 25.44±14.00 | 0.0014 |
| TNFAIP2 | 43.07±32.67 | 58.23±22.33 | 0.0766 |
| VCAN | 29.51±16.21 | 36.24±17.02 | 0.1648 |
| ASS1 | 7.83±4.05 | 11.41±4.52 | 0.0052 |
| HK3 | 2.38±2.10 | 2.64±0.88 | 0.5554 |
| TNF-α | 13.25±27.38 | 3.76±2.02 | 0.0686 |
| IL-1β | 10.10±17.02 | 1.59±0.99 | 0.0105 |
| LPL | 13.69±15.62 | 8.12±5.90 | 0.0839 |
| IRF1 | 16.34±13.14 | 17.68±6.57 | 0.6352 |
| STAT | 16.15±10.60 | 17.47±8.79 | 0.6481 |
| IRG1 | 6.51±7.33 | 5.77±4.25 | 0.6528 |
| TLR2 | 8.34±7.68 | 12.32±16.93 | 0.3339 |
| SERPING1 | 12.91±9.83 | 17.22±23.15 | 0.4399 |
| UBD | 29.79±20.00 | 22.18±12.45 | 0.1038 |
| CXCL10 | 5.11±10.91 | 2.88±3.06 | 0.2959 |
| TLR4 | 27.07±52.19 | 16.31±7.54 | 0.2746 |
| IL-6 | 478.52±2573.30 | 7.49±4.29 | 0.3244 |
| CXCL11 | 22.03±42.62 | 13.92±12.43 | 0.3329 |
These 19 genes were selected for analysis based on previous animal experimental data. TFEC, transcription factor EC; CCL2, chemokine (C-C motif) ligand 2; TNFAIP2, tumor necrosis factor-α-induced protein 2; VCAN, versican; ASS1, argininosuccinate synthetase 1; HK3, hexokinase 3; TNF-α, tumor necrosis factor-α; IL-1β, interleukin 1β; LPL, lipoprotein lipase; IRF1, interferon regulatory factor 1; STAT, signal transducer and activator of transcription 1; IRG1, immunoresponsive gene 1; TLR2, toll-like receptor 2; SERPING1, serine peptidase inhibitor, clade G, member 1; UBD, ubiquitin D; CXCL10, chemokine (C-X-C motif) ligand 10; TLR4, toll-like receptor 4; IL-6, interleukin 6; CXCL11, chemokine (C-X-C motif) ligand 11. Student's t test was employed.