Table 1.
Characteristics of subjects with FT3 tertiles
| Parameters | Men |
Women |
||||||
|---|---|---|---|---|---|---|---|---|
| FT3 tertiles |
FT3 tertiles |
|||||||
| T1 | T2 | T3 | p for trend | T1 | T2 | T3 | p for trend | |
| N | 148 | 149 | 148 | − | 197 | 198 | 196 | − |
| Age, years | 63 (58−67) | 59 (54−64) | 58 (52−63) | <0.001 | 60 (53−64) | 59 (55−63) | 58 (53−62) | 0.236 |
| BMI, kg/m2 | 23.68 (21.93−25.77) | 24.13 (22.36−25.85) | 24.65 (22.92−26.38) | 0.038 | 22.66 (21.04−25.05) | 23.31 (21.14−25.47) | 23.46 (21.41−25.73) | 0.072 |
| FT4, pmol/L | 16.31 (15.22−17.59) | 16.74 (15.39−17.99) | 17.29 (15.91−18.56) | <0.001 | 15.99 (14.88−17.13) | 16.37 (15.11−17.40) | 16.87 (15.36−17.92) | <0.001 |
| TSH, mIU/L | 2.09 (1.52−2.77) | 2.01 (1.47−2.66) | 2.04 (1.41−2.74) | 0.667 | 2.31 (1.64−3.18) | 2.28 (1.59−3.00) | 2.20 (1.64−2.87) | 0.426 |
| TC, mmol/L | 5.38±0.93 | 5.09±0.82 | 5.08±0.85 | 0.003 | 5.68±0.99 | 5.74±1.05 | 5.4±0.94 | 0.003 |
| TG, mmol/L | 1.46 (1.01−2.27) | 1.45 (1.06−2.18) | 1.56 (1.01−2.40) | 0.927 | 1.20 (0.89−1.69) | 1.29 (0.91−1.83) | 1.25 (0.89−1.68) | 0.529 |
| HDL-c, mmol/L | 1.34 (1.08−1.55) | 1.21 (1.06−1.47) | 1.21 (1.08−1.41) | 0.067 | 1.56 (1.34−1.81) | 1.52 (1.30−1.78) | 1.49 (1.27−1.73) | 0.178 |
| LDL-c, mmol/L | 3.26±0.86 | 3.10±0.68 | 3.14±0.73 | 0.175 | 3.46±0.87 | 3.51±0.89 | 3.25±0.81 | 0.008 |
| SBP, mm Hg | 131.50 (121.00−142.00) | 131.00 (120.00−142.00) | 134.00 (123.00−145.00) | 0.394 | 122.00 (111.00−134.00) | 125.00 (113.00−138.00) | 125.00 (115.00−138.75) | 0.041 |
| DBP, mm Hg | 79.00 (73.00−86.00) | 80.00 (73.00−87.00) | 82.00 (74.25−88.00) | 0.113 | 73.00 (67.50−80.00) | 74.00 (69.00−82.00) | 77.00 (69.00−83.00) | 0.026 |
| HOMA-IR | 1.84 (1.22−2.80) | 2.05 (1.37−2.97) | 2.18 (1.60−3.55) | 0.010 | 1.95 (1.40−2.71) | 2.18 (1.59−3.11) | 2.45 (1.66−3.72) | 0.001 |
| HbA1c, % | 5.60 (5.30−5.80) | 5.60 (5.40−5.90) | 5.60 (5.40−5.90) | 0.732 | 5.70 (5.40−5.90) | 5.70 (5.50−6.00) | 5.70 (5.50−5.98) | 0.407 |
| FINS, mlU/L | 7.27 (4.91−10.41) | 8.08 (5.43−11.33) | 8.83 (6.46−13.23) | 0.003 | 7.82 (5.89−10.96) | 8.46 (6.09−12.11) | 9.49 (6.73−13.35) | 0.002 |
| FPG, mmol/L | 5.75 (5.42−6.24) | 5.68 (5.33−6.13) | 5.67 (5.32−6.12) | 0.268 | 5.50 (5.24−5.95) | 5.67 (5.34−6.09) | 5.76 (5.38−6.15) | 0.002 |
| 2hPG, mmol/L | 7.47 (5.78−9.22) | 7.00 (5.75−8.35) | 7.02 (5.74−8.63) | 0.340 | 7.12 (5.81−8.61) | 7.01 (5.94−8.28) | 6.88 (5.56−8.94) | 0.783 |
| Current smokers, n (%) | 43.2 (64) | 54.4 (81) | 56.1 (83) | 0.056 | 1.0 (2) | 1.0 (2) | 1.0 (2) | 0.996 |
Data are means ± standard deviation or medians with interquartile ranges in parentheses. 2hPG, 2-h plasma glucose; BMI, body mass index; DBP, diastolic blood pressure; FPG, fasting plasma glucose; FT3, free triiodothyronine; FT4, free thyroxine; FINS, fasting insulin; HDL-c, high-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment-insulin resistance; HbA1c, glycated hemoglobin A1e; LDL-c, low-density lipoprotein cholesterol; SBP, systolic blood pressure; SFA, subcutaneous fat area; TC, total cholesterol; TG, triglyceride; TSH, thyroid-stimulating hormone. T1 <5.02 pmol/L, T2 5.02–5.38 pmol/L, and T3 >5.38 pmol/L for men; T1 <4.57 pmol/L, T2 4.57–4.93 pmol/L, and T3 >4.93 pmol/L for women.