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Maximum intensity projections of PET images from NBA (upper row, group B1) and biotin-challenged (lower row, group B1) mice receiving [11C]biotin OG at (A, D) 0–3 min, (B, E) 5–10 min, and (C, F) 60–80 min after the start of the PET imaging study. PET images are displayed according to the intensity scale for tracer activity, from white (highest) through red (intermediate) to purple (lowest). Stomach, intestine, urinary bladder, liver, kidneys and BAT are indicated where visible.
