Table 1.

Summary of Incidence, Prevalence or Outcomes Data for Breast Cancer in Asia

Country	References	Reported data
China	Zhou HB, et al.(Zhou et al., 2015); Wu LZ, et al.(Wu et al., 2014b); Shi XJ, et al.(Shi et al., 2014b); Zhang X, et al.(Zhang et al., 2013b); Li XP, et al.(Li et al., 2013b)	- Crude incidence rate of 20.0 / 100,000 population between 2007 and 2012. - The age-standardized rate was 21.1 / 100,000 in 2012. - Average annual percentage change of 11.3%. - Mortality rate has increased yearly since 1991, a trend predicted to continue over the following 5 years. - After median 60 months of follow-up (range, 8–60 months), local and distant recurrence of breast cancer was observed in 23.4% of cases. - Between 2002 and 2006, the 5-year relative survival rate for breast cancer was > 40%. In Jiangsu between 2006 and 2010: - 11,013 new cases of female breast cancer and 3,068 deaths due to female breast cancer were identified. - The annual average crude incidence and age-standardized incidence were 25.2 and 17.9 per 100,000, and mortality rates were 7.03 and 4.81 per 100,000 respectively. - Incidence and mortality increased with annual percentage changes of 4.47% and 6.89%, respectively.
Japan	Hori M, et al.(Hori et al., 2015); Sugawara Y, et al.(Sugawara et al., 2013); Kasahara Y, et al.(Kasahara et al., 2013); Yamashiro H, et al.(Yamashiro et al., 2014); Matsuda A, et.al.(Matsuda et al., 2014); Wada K, et.al.(Wada et al., 2014)	- Leading type of cancer in females. - Primary invasive cancer incidence 775,601 in 2009. - Of 26,680 women, 148 incident cases of breast cancer were identified during 11 years of follow-up. - The rate of breast cancer detected in women aged 40–49 years was 0.28%. - Bone metastases developed in 11.3% (n=193) of recently diagnosed breast cancer cases - The bone-metastasis-free rate at 5 years was 89.2%.
Hong Kong	Kwong A, et al.(Kwong et al., 2014); Wong IO, et al.(Wong et al., 2015)	- Mean age at diagnosis of breast cancer in male and female patients was 64.5 and 52.7 years, respectively. - The 5-year OS, breast-cancer-specific mortality, and DFS for male and female patients were 78.7%, 90.5%, 90.5%, and 77.9%, 86.4%, and 81.4% respectively. - Age-standardized incidence projected to increase from 56.7 per 100,000 women in 2011–2015 to 62.5 per 100,000 women in 2021–2025. - Age-standardized mortality projected to decrease from 9.3 to 8.6 per 100,000 women for the same periods.
Korea	Park YH, et al.(Park et al., 2015b); Kim JH, et al.(Kim et al., 2014); Jung M, et al.(Jung et al., 2013)	- During a median follow-up of 100 months, the 5-year RFS rate and OS rate were 90.8% and 94.6%, respectively. - The 10-year estimated RFS rate and OS rate were 81.9% and 86.9%, respectively. - After median follow-up of 82 months, 5-year local RFS was 98.4% and the 10-year local RFS was 95.8% for all patients. Nineteen patients (2.6%) had ipsilateral breast recurrences, including 12 invasive recurrences and seven DCIS. Nine patients (1.2 %) patients developed contralateral breast cancer, including six invasive breast cancer and three DCIS. - The observed 10-year OS, breast cancer-specific survival and event-free survival was 61.4%, 62.3% and 59.1%, respectively.
Thailand	Virani S, et al.(Virani et al., 2014); Kotepui M, et.al.(Kotepui et al., 2014)	- Age-adjusted incidence rate increased by almost 300% from 1990 to 2010. - Incidence rates increased from 10.0 to 27.8 cases per 100,000 person-years. - Benign breast disease and fibroadenoma occurred in women aged < 40 years whereas breast cancer occurred in women aged > 40 years (OR: 8.629; 95% CI: 6.939–10.729; P < 0.001 and OR: 23.906; 95% CI: 18.359–31.129; P < 0.001, respectively). - Fibrocystic change occurred in patients aged < 40 years whereas breast cancer commonly occurred in patients aged ≥ 40 years (OR: 3.865; 95% CI: 2.993–4.991; P < 0.001).
India	Asthana S, et al.(Asthana et al., 2014)	- The annual percentage change in incidence for breast cancer ranged from 0.46% to 2.56%.
Asia	Keramatinia A, et al.(Keramatinia et al., 2014)	- 23,661 cases of breast cancer occurred in the 10 analyzed registries over 32 years of follow-up (1970–2002).
Malaysia	Hassan N, et al.(Hassan et al., 2015)	- Of the Chinese women in this study, 99.2% had a 10-year risk of breast cancer of < 2%.
Vietnam	Lan NH, et al.(Lan et al., 2013)	- OS rates at 1, 3, and 5 years following diagnosis were 0.94, 0.83 and 0.74 respectively.

DFS, disease-free survival; OS, overall survival; RFS, recurrence-free survival.