Table 2.
Binding Energy Values of Stigmasterol which were Used for Various Cancer Receptors
| Receptors | Compound name |
Parameters |
||||
|---|---|---|---|---|---|---|
| Binding energy (kcal/mol) |
Number of Hydrogen bonds |
Amino acid residues |
Number of Hydrophobic Interactions |
Amino acid residues | ||
| 1M17 | stigmasterol | -9.98 | 2 | GLU-738, GLU-738 |
9 | LEU- 694, LEU- 694, VAL-702, LYS-721, THR-766, LEU-768, LYS-242, MET-769, LEU-820, LEU-820 |
| Gefitinib | -8.02 | 3 | THR-766, THR-766, MET-679 |
7 | LEU- 694, VAL-702, VAL-702, ALA-719,LEU-768, MET-769, LEU-820 | |
| 1T46 | stigmasterol | -11.97 | 1 | ILE-571 | 11 | ILE-571, PRO-573, GLU-640, VAL-643, LEU-644, LEU-644, ILE-644, ILE-653, VAL-654, ILE-808 |
| Imatinib | -13.84 | 4 | GLU-640, THR-670, ILE-789, ASP-810 |
11 | VAL-603, ALA 621, LYS-623, LEU-644, LEU-644, ILE-6653, VAL-668, THR-670, TYR-672, LEU-799, ASP-810 | |