Table 2.
Performance comparison of the two systems at a positive MRI cut-off of score ≥3 for csPCa (Gleason score ≥3 +4)
| Score | Sensitivity (95% CI) |
Specificity (95% CI) |
PPV (95% CI) |
NPV (95% CI) |
Accuracy (95% CI) |
AUC* (CI 95%) |
|---|---|---|---|---|---|---|
| Likert | 0.94 (0.85–0.98) |
0.77 (0.69–0.84) |
0.66 (0.56–0.76) |
0.96 (0.91–0.99) |
0.82 (0.76–0.87) |
0.92 (0.87–0.95) |
| PI-RADS | 0.94 (0.85–0.98) |
0.66 (0.58–0.74) |
0.58 (0.48–0.67) |
0.96 (0.89–0.99) |
0.75 (0.69–0.81) |
0.87 (0.82–0.92) |
AUC, area under the curve; CI, confidence interval; NPV, negative predictive value; PI-RADS, Prostate Imaging–Reporting and Data System; PPV, positive predictive value; csPCa, clinically significant prostate cancer.
*p = 0.002 demonstrates significant difference between the two systems.