Table 1.
Comparison of the clinical and laboratory features between confirmed patients with COVID-19 and SARS-CoV-2-negative patients
| Characteristics | Confirmed patients (N = 12) | Negative patients (N = 16) | P values |
| Age, years, median (IQR) | 40 (30–61） | 35 (21–53) | 0.265 |
| Sex | 0.243 | ||
| Females(n, %) | 6 (50.0) | 4 (25.0) | |
| Males(n, %) | 6 (50.0) | 12 (75.0) | |
| Chronic medical illness(n, %) | 4 (33.3) | 4 (25.0) | 0.691 |
| Signs and symptoms | |||
| Fever(n, %) | 12 (100) | 13 (81.2) | 0.238 |
| Cough(n, %) | 9 (75.0) | 15 (93.7) | 0.285 |
| Shortness of breath(n, %) | 2 (16.6) | 2 (12.5) | 1 |
| Myalgia(n, %) | 11 (91.6) | 5 (31.2) | 0.002 |
| Sore throat(n, %) | 1 (8.3) | 2 (12.5) | 1 |
| Diarrhoea(n, %) | 2 (16.6) | 4 (25.0) | 0.673 |
| Nausea and vomiting(n, %) | 3 (25.0) | 3 (18.75) | 1 |
| Epidemiological survey | |||
| History of stay in Wuhan(n, %) | 8 (66.6) | 4 (25.0) | 0.053 |
| Contact with Wuhan residents(n, %) | 11 (91.6) | 10 (62.5) | 0.184 |
| Cluster outbreak(n, %) | 6 (50.0) | 4 (25.0) | 0.243 |
| Blood routine | |||
| Leucocytes (×109/L, normal range 3.5–9.5) | 4.9 (4.3–6.9) | 6.8 (5.4–9.1) | 0.095 |
| Neutrophils (×109/L, normal range 1.8–6.3) | 3.2 (2.7–3.8) | 4.6 (3.4–6.1) | 0.029 |
| Lymphocytes (×109/L, normal range 1.1–3.2) | 1.2 (1.0–1.7) | 1.0 (0.7–1.8) | 0.246 |
| Platelets (×109/L, normal range 125.0–350.0) | 189.5 (144.7–223.7) | 197.5 (154.7–253.2) | 0.546 |
| Haemoglobin (g/L, normal range 130.0–175.0) | 143.0 (133.5–149.7) | 138.5 (123.2–148) | 0.416 |
| Blood biochemistry | |||
| Alanine aminotransferase (U/L, normal range 3.0–35.0) | 14.5 (12.2–23.7) | 23.0 (14.5–50.7) | 0.21 |
| Total bilirubin (μmol/L, normal range 4.0–23.9) | 7.3 (4.9–11.6) | 8.1 (6.1–15.2) | 0.39 |
| Albumin (g/L, normal range 36.0–51.0) | 47.5 (41.5–49.0) | 44.5 (34.6–49.8) | 0.21 |
| Erythrocyte sedimentation rate (mm/h, normal range 0–15) | 12.5 (7.0–30.5) | 13.0 (6.0–35.0) | 0.807 |
| C-reaction protein (mg/L, normal range 0–6) | 8.1 (6.7–28.2) | 13.5 (2.2–106.8) | 0.889 |
| Procalcitonin (ng/mL, normal range 0–0.05) | 0.03 (0.02–0.06) | 0.08 (0.03–0.19) | 0.064 |
Data are n (%) and median(IQR). IQR=interquartile range. N is the total number of patients withavailable data. SARS-CoV-2=severe acuterespiratory syndrome coronavirus 2. P values for the comparisons between two groups were derived using Fisher’s exact test for categorized variables and the Mann-Whitney U test for continuous variables.