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Bone involvement in RMS can be either (a) sclerotic, permeative and poorly FDG-avid or (b) lytic and markedly FDG-avid at 18F-FDG PET (arrow). In lytic lesions, (c) percutaneous cementoplasty (arrow) can be performed to achieve pain relief, like in the case of this 52-year-old female with pleomorphic RMS and osteoporosis. 18F-FDG, 18F-fludeoxyglucose; PET, positron emision tomography; RMS, rhabdomyosarcomas.
