Figure 2.
18F-FDG PET-MR imaging in a female patient with pancolitis 18F-FDG PET-MR imaging revealed active pancolitis in a female patient with endoscopically moderate disease activity. The fecal levels of calprotecin, lactoferrin, PMN-e, S100A12 and EDN were 37.43, 46.92, 0.06, 90.14, 3.27, while the SUVmean was 1.93. According to the optimal cut-off values (Table 4), only EDN and SUVmean correctly predicted the endoscopically disease activity. (A) Hyperintense mucosal layer and wall thickness in the T2 weighted imaging demonstrating mucosal edema in the ascending and descending colon (black arrows). (B) Hyperintense appearance of mucosal layer (white arrow) and adjacent comb sign indicating hyperemia in the contrast-supported T1 weighted imaging with fat-saturation. (C) Fused imaging of PET and MR. (D) Hyperintensity of bowel wall shown in the b1000 of diffusion-weighted imaging. (E) PET. (F) Maximum intensity projection of PET in the coronal plane demonstrating enhanced 18F-FDG-uptake of the whole colorectumcompared to liver. EDN, eosinophil-derivedneurotoxin; 18F-FDG, 18F-fludeoxyglucose; PET, positronemission tomography; PMN-e, polymorphonuclear leukocyte elastase; SUVmean, mean value of maximum of standardized uptakevalue ratio gut/liver.