Table 2.

Summary of procedures

Time	Source	Sample	Tests to perform	Storage requirements
Postpartum period (Consent/ Assent A)	Maternal venous blood	5 ml EDTA for plasma	ELISA and IHA	Filter paper 4 °C Plasma/serum − 20 °C
4–8 weeks postpartum	Home visit to provide consent to be randomized (Consent/Assent B)
Before randomization	Clinical assessment
6 months postpartum	Randomization to BZN 30d/150 mg (intervention arm) or BZN 60d/300 mg (control arm)
Before treatment	Maternal venous blood	5 ml	PCR	10 ml blood-Guanidine 4 °C
Once a week	Monitoring adverse events
During treatment	Maternal finger prick/ venous blood	DBS	BZN concentration	Filter paper −20 °C
End of treatment	Maternal venous blood	5 ml	PCR	10 ml blood-Guanidine 4 °C
10 months after treatment	Maternal venous blood	5 ml	PCR	10 ml blood-Guanidine 4 °C