Table 1.

Changes in psychological profile in patients who attended visit 3 (communication of genetic results)

		Baseline Visit 1 N=12	communication of results Visit 3 N=12	P-value*
Anxiety (Spielberger)	Trait (20–80)*	33.0 [25.3;40.5]	36 [23.8;40.0]	0.722
	State (20–80)*	42.5 [31.9;47.0]	40.5 [27.5;45.8]	0.028
Mood disorders (BDI)	T otal score (0–39)**	4.5 [1.3;6.0]	2.5 [1.3;5.0]	0.572
Quality of life(SF-36)***	Physical functioning	85 [72.5;95]	90 [56.3;95.0]	0.287
	Social functioning	56.3 [50;97.0]	81.3 [62.5; 100]	0.135
	Role physical	25 [0;91.7]	87.5 [6.0; 100]	0.078
	Role emotional	41.7 [0;91.7]	100 [8.3;100]	0.206
	Mental health	64.0 [48.0;83.0]	72.0 [57.0;88.0]	0.133
	Vitality	45.0 [35.0;60.0]	65.0 [36.3;75.0]	0.005
	Bodily pain	61.5 [43.5;81.5]	73.0 [46.0;81.5]	0.760
	General health	57.0 [37.8;79.5]	77.0 [52.0;82.0]	0.026
	Mental composite score	43.6 [30.8;52.9]	48.8 [39.9;52.1]	0.060
	Physical composite score	47.8 [38.6;51.9]	49.3 [39.0;58.5]	0.754
Psychological consequences of testing (PCQ)	Total score (0–10)****	4.6 [3.6–5.4]	4.0 [2.8–4.7]	0.168

^*paired test between baseline visit (visit 1) and visit 3

BDI Beck Depression Inventory. SF-36 Short-Form 36, PCQ Psychological Consequences of Screening

^*higher score. higher anxiety level

^**higher score. higher mood disorder level

^***higher score. better quality of life

^****higher score, higher negative psychological consequence