Fig. 8.

Effects of RDN and COL on the protein levels of rPPARγ and rAdipoR2 in the joint-synovial tissue of GA rats. RDN and COL were given 3 days before the models were induced every 24 h. The normal group and the model group were given normal saline at the same time. MSU solution was injected into both knees after intraperitoneal injection of 10% chloral hydrate to anaesthetize the rats an hour after the drugs were given since the third day. The drugs were given for 7 days continuously while the models were induced for 5 days altogether. 1.Normal group, 2. Model group,3. RDN high group, 4. RDN middle group, 5. RDN low group, 6. COL group