Fig. 2.

CREB5 activates the MET signalling pathway. a GSEA of GSE17538 in MET signalling pathways (ES = 0.43, p < 0.01). b Stable overexpression and interference cell lines were detected by western blotting and real-time PCR. c The expression of MET and downstream signalling molecules in CREB5-knockdown or CREB5-overexpressing cells was observed by western blotting. d CREB5 had an effect on MET by real-time PCR in the indicated cells. e After transient transfection of different amounts of the CREB5-overexpression plasmid in SW480 cells, the protein and mRNA levels of MET were detected by western blotting and real-time PCR, respectively. ** p < 0.01