Table 2.
The diagnostic performance for each included study
| Indicator | Author | Year | Threshold | AUC | Sensitivity | Specificity | TP | FP | FN | TN |
|---|---|---|---|---|---|---|---|---|---|---|
| ADC | Deng et al. [7] | 2015 | 1.0224 | 0.833 | 0.733 | 0.875 | 22 | 1 | 8 | 7 |
| Huang et al. [13] | 2016 | 1.547 | 0.805 | 0.889 | 0.667 | 27 | 5 | 3 | 10 | |
| Jiang et al. [8] | 2020 | 1.46 | 0.805 | 0.9245 | 0.6316 | 81 | 12 | 7 | 21 | |
| Wan et al. [9] | 2018 | 1.734 | 0.773 | 0.793 | 0.749 | 55 | 5 | 14 | 15 | |
| Wang Y et al. [11] | 2019 | 1.265 | 0.847 | 0.847 | 0.715 | 25 | 6 | 5 | 14 | |
| Yuan et al. [15] | 2015 | 1.31 | NA | 0.812 | 0.812 | 42 | 9 | 10 | 39 | |
| Zhou et al. [12] | 2018 | 1.57 | 0.708 | 0.905 | 0.591 | 38 | 9 | 4 | 13 | |
| D | Huang et al. [13] | 2016 | 1.04 | 0.93 | 0.944 | 0.75 | 28 | 4 | 2 | 11 |
| Jiang et al. [8] | 2020 | 1.23 | 0.882 | 0.9057 | 0.8947 | 80 | 3 | 8 | 30 | |
| Jiao et al. [10] | 2019 | 0.958 | 0.812 | 0.763 | 0.78 | 45 | 8 | 14 | 29 | |
| Wan et al. [9] | 2018 | 1.138 | 0.834 | 0.8551 | 0.75 | 59 | 5 | 10 | 15 | |
| Wang LL et al. [14] | 2014 | 0.98 | 0.763 | 0.871 | 0.665 | 27 | 10 | 4 | 21 | |
| Wang Y et al. [11] | 2019 | 1.185 | 0.888 | 0.888 | 0.752 | 27 | 5 | 3 | 15 | |
| Yuan et al. [15] | 2015 | 1.44 | NA | 0.913 | 0.385 | 47 | 30 | 5 | 18 | |
| Zhou et al. [12] | 2018 | 1.25 | 0.729 | 0.952 | 0.545 | 40 | 10 | 2 | 12 | |
| Wang XH et al. [20] | 2014 | 0.9 | 0.839 | 0.957 | 0.8 | 22 | 3 | 1 | 12 | |
| D* | Deng et al. [7] | 2015 | NA | 0.679 | 0.622 | 0.8 | 19 | 2 | 11 | 6 |
| Huang et al. [13] | 2016 | 17.935 | 0.605 | 0.765 | 0.462 | 23 | 8 | 7 | 7 | |
| Jiang et al. [8] | 2020 | 15.9 | 0.696 | 0.7925 | 0.6316 | 70 | 12 | 18 | 21 | |
| Wan et al. [9] | 2018 | NA | NA | 0.693 | 0.45 | 48 | 11 | 21 | 9 | |
| Yuan et al. [15] | 2015 | 12.71 | NA | 0.478 | 0.692 | 25 | 15 | 27 | 33 | |
| Zhou et al. [12] | 2018 | 8.82 | 0.68 | 0.714 | 0.591 | 30 | 9 | 12 | 13 | |
| Wang XH et al. [20] | 2014 | 3.7 | 0.683 | 0.826 | 0.6 | 19 | 6 | 4 | 9 | |
| f | Deng et al. [7] | 2015 | 37.43% | 0.829 | 0.8 | 0.75 | 24 | 2 | 6 | 6 |
| Huang et al. [13] | 2016 | 28.35% | 0.615 | 0.75 | 0.429 | 23 | 9 | 7 | 6 | |
| Wan et al. [9] | 2018 | NA | NA | 0.719 | 0.5 | 50 | 10 | 19 | 10 | |
| Wang LL et al. [14] | 2014 | 24.93% | 0.762 | 0.806 | 0.548 | 25 | 14 | 6 | 17 | |
| Yuan et al. [15] | 2015 | 18.36% | NA | 0.609 | 0.692 | 32 | 15 | 20 | 33 | |
| Wang XH et al. [20] | 2014 | 39.30% | 0.639 | 0.521 | 0.8 | 12 | 3 | 11 | 12 |
NA Not available, ADC Apparent diffusion coefficient, D Tissue diffusivity, D* pseudo-diffusivity, f Perfusion fraction, AUC Area under the curve, FN False negative, FP False positive, TN True negative, TP True positive. Threshold values of ADC, D and D* are factors of 10− 3 mm2/s