Table 3.

Pooled estimates and heterogeneity measures for ADC, D, D* and f values

Index	Sensitivity	Specificity	PLR	NLR	DOR	AUC	I2 (%)
							Sensitivity	Specificity
ADC	0.85 (0.79,0.90)	0.72 (0.63,0.80)	3.1 (2.3,4.1)	0.20 (0.15,0.28)	15 (9,24)	0.86 (0.83,0.89)	43.07	3.91
D	0.89 (0.85,0.93)	0.71 (0.59,0.81)	3.1 (2.1,4.5)	0.15 (0.10,0.22)	20 (11,38)	0.90 (0.88,0.93)	44.52	77.62
D*	0.70 (0.62,0.78)	0.60 (0.52,0.68)	1.8 (1.4,2.2)	0.49 (0.37,0.65)	4 (2,6)	0.66 (0.62,0.70)	68.04	0
f	0.71 (0.62,0.78)	0.61 (0.49,0.71)	1.8 (1.4,2.3)	0.48 (0.37,0.62)	4 (2,6)	0.71 (0.67,0.75)	45.99	40.89

ADC Apparent diffusion coefficient, D Tissue diffusivity, D* Pseudo-diffusivity, f Perfusion fraction, PLR Positive likelihood ratio, NLR Negative likelihood ratio, DOR Diagnostic odds ratio, AUC Area under the curve; I², inconsistency index