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. 2020 Aug 18;11:2041731420945633. doi: 10.1177/2041731420945633

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© The Author(s) 2020

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — Technical sketches and color maps of the numerical characterization of the chambers hosting 1.25-mm-thick COLL-PEG₂₀₀₀ gels (embedded condition, 3.125 × 10⁵ cells/cm², 1:10 v/v). We reported the values of the parameters used for the simulation in Table 1. (a) Overall and (b) side view of the geometry. From top to bottom, it comprised four domains: the upper perfusion channel of the hydrogel chamber, the hydrogel (light blue), the membrane, and the other perfusion channel. (c) Top view and (d) side view of the color map showing the distribution of oxygen concentration. (e) Top view and (f) side view of the color map showing the distribution of shear stresses.