Fig A3.

Disease-free survival (DFS) for cell-free DNA (cfDNA) single nucleotide variant (SNV) load and burden in patients with stage IV melanoma (cohort 1). The Kaplan-Meier curves for (A) two cfDNA SNV load groups and for (C) two cfDNA SNV burden groups with the fitted (dashed lines) Gompertz curves. (B and D) The difference in mean DFS for the two patient groups (gray area) is shown. The end point for DFS is the time to event related to the disease itself or death from a disease-specific event (ie, noncancer deaths are censored).