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. 2019 Oct 1;3:PO.19.00232. doi: 10.1200/PO.19.00232

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FIG 2. — SMART (Sustainable Medical Apps, Reusable Technology) Precision Cancer Medicine (PCM) architecture diagram. The application is designed to be modular and extensible, particularly in the ability to add presentation modules and interfaces to external data sources. External sources with the Fast Healthcare Interoperability Resources (FHIR) logo can expose information using native FHIR; others require some degree of custom mapping. API, application programming interface; CIViC, Clinical Interpretations of Variants in Cancer; JAX-CKB, Jackson Laboratory Clinical Knowledgebase; LDAP SSO, Lightweight Directory Access Protocol Single Sign-On; NGS, next-generation sequencing; PMKB, Precision Medicine Knowledgebase.