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. 2018 May 17;2:PO.17.00279. doi: 10.1200/PO.17.00279

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© 2018 by American Society of Clinical Oncology

Licensed under the Creative Commons Attribution 4.0 License: http://creativecommons.org/licenses/by/4.0/

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Fig 3. — Analysis of circulating tumor DNA (ctDNA) in patients with liver metastasis. (A) Comparison of ctDNA levels in patients with primary (n = 27) and metastatic (n = 8) uveal melanoma (UM) showed statistically significant differences (Student t test, P < .001). (B) Plasma ctDNA levels in longitudinally collected samples from patient 656 with UM. (C) Plasma ctDNA levels in longitudinally collected samples from patient 433 with UM, before and after the development of overt metastatic disease as shown by fluorodeoxyglucose–positron emission tomography imaging of the liver. NAD, no active disease; PD, progressive disease. (*) Resection of a solitary liver metastasis.