Outcomes of BRAF V600E–mutated pediatric high-grade gliomas (PHGGs) treated with BRAF inhibition. (A) Waterfall plot of best response, (B) swimmer plot, and (C) Kaplan-Meier plot for progression-free survival (PFS) comparing children with pediatric low-grade glioma (PLGG) and PHGG. CR, complete response; MR, minor response; PD, progressive disease; PR, partial response; SD, stable disease.