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Histologic features at diagnosis. (A) Hematoxylin and eosin stain (40× magnification). (B) Hematoxylin and eosin stain (20× magnification).Tumor sample demonstrating an infiltrative cellular astrocytic neoplasm with fibrillary background, nuclear atypia, mitoses, and vascular proliferation; consistent with glioblastoma, WHO grade 4.
