TABLE 2.
CSF Culture Time to Positivity by Demographics and Clinical Characteristics
| Pathogens | Contaminants | Pathogen-Contaminant Comparison | |||||
|---|---|---|---|---|---|---|---|
| n (%) | Time to Positivity, Median (IQR), h | Pa | n (%) | Time to Positivity, Median (IQR) | Pa | Pa | |
| Total population | 22 | 14.0 (1.5–21.0) | — | 51 | 40.5 (21.2–62.6) | — | <.001 |
| Sex | .071 | .435 | |||||
| Male | 11 (50.0) | 21.0 (1.5–39.8) | — | 37 (72.5) | 39.1 (21.2–62.3) | — | 0.034 |
| Female | 11 (50.0) | 8.2 (1.3–18.7) | — | 14 (27.5) | 52.0 (29.6–83.3) | — | <.001 |
| Age group, d | .481 | .027 | |||||
| 0–28 | 17 (77.3) | 8.2 (1.3–20.8) | — | 18 (35.3) | 24.7 (17.3–50.8) | — | .021 |
| 29–60 | 5 (22.7) | 18.7 (11.9–21.0) | — | 33 (64.7) | 46.4 (37.0–67.3) | — | .002 |
| Race category (white, Black, other) | .787 | .506 | |||||
| White | 8 (40.0) | 9.0 (1.0–30.3) | — | 30 (61.2) | 38.9 (28.9–54.2) | — | .013 |
| Black or African American | 9 (45.0) | 3.4 (1.5–22.5) | — | 12 (24.5) | 62.0 (25.3–97.9) | — | .002 |
| Other | 3 (15.0) | 18.7 (11.9–20.2) | — | 7 (14.3) | 58.0 (9.8–90.5) | — | .569 |
| Ethnicity | .592 | .120 | |||||
| Hispanic or Latino | 6 (30.0) | 17.4 (8.2–21.0) | — | 16 (32.7) | 38.9 (19.2–47.5) | — | .090 |
| Not Hispanic or Latino | 14 (70.0) | 7.7 (1.3–20.8) | — | 33 (67.3) | 50.8 (22.9–67.3) | — | <.001 |
| Categories of date and time of ED discharge | .285 | .165 | |||||
| 00:00–08:00 | 5 (22.7) | 1.9 (1.1–8.2) | — | 13 (25.5) | 62.6 (30.9–103.3) | — | .005 |
| 08:00–16:00 | 6 (27.3) | 10.8 (0.7–21.0) | — | 11 (21.6) | 43.3 (28.9–58.0) | — | .004 |
| 16:00–24:00 | 11 (50.0) | 18.7 (3.4–39.8) | — | 27 (52.9) | 38.7 (19.7–61.8) | — | .055 |
| Duration of fever before ED visit | .255 | .420 | |||||
| <12 h | 10 (58.8) | 12.2 (1.5–20.8) | — | 26 (63.4) | 47.5 (28.9–83.3) | — | .001 |
| 12–24 h | 4 (23.5) | 19.4 (9.6–22.8) | — | 14 (34.1) | 38.2 (19.0–42.2) | — | .089 |
| >24 h | 3 (17.6) | 0.9 (0.7–11.9) | — | 1 (2.4) | 66.4 (66.4–66.4) | — | .180 |
The variable race category had 2 missing values for pathogens and 2 missing values for contaminants. The variable ethnicity had 2 missing values for pathogens and 2 missing values for contaminants. The variable duration of fever had 5 missing values for pathogens and 10 missing values for contaminants. —, not applicable.
a
Kruskal–Wallis test for comparing ≥3 groups. Wilcoxon rank test without continuity correction for comparing 2 groups.