Table 1.
Demographic and clinical information about the REF and iNPH cohorts at the time MRI.
| REF | iNPH | Significance | |
|---|---|---|---|
| N | 8 | 9 | |
| Sex (F/M) | 6/2 | 1/8 | 0.008 |
| Age (years) | 38.4 ± 17.3 | 68.3 ± 9.5 | <0.001 |
| Symptoms reported by patient and/or family | |||
| Gait disturbance | 2 (25%) | 9 (100%) | 0.001 |
| Urinary incontinence | 0 (0%) | 6 (67%) | 0.004 |
| Cognitive impairment | 0 (0%) | 8 (89%) | <0.001 |
| Duration of symptoms (months) | 42.4 ± 40.6 | 21.3 ± 10.4 | ns |
| NPH score | 15 (14–15) | 13 (11–13) | <0.001 |
Note: Categorical data presented as numbers; continuous data presented as mean ± standard deviation. Significant differences between groups were determined by Pearson Chi-square test for categorical data and by independent samples t-test for continuous data.
iNPH: idiopathic normal pressure hydrocephalus; REF: reference patients.