Table 1.
Patient characteristics.
All COVID-19 patients |
COVID-19 patients without PE |
COVID-19 patients with PE |
P value | |
---|---|---|---|---|
(n = 70) | (n = 66) | (n = 4) | ||
Age (years) | 65 ± [21–97] | 65 ± 16 [21–97] | 69 ± 3 [66–73] | 0.226 |
Male | 44/70 (63) | 41/66 (62) | 3/4 (75) | 1.0 |
Positive RT-PCR | 65/70 (93) | 61/66 (92) | 4/4 (100) | 1.0 |
Delay from onset of symptoms to CT (days) | 8 ± 4 [1–16] | 8 ± 4 [1–16] | 6 ± 2 [4–8] | 0.354 |
Comorbidities | ||||
Overweight or obesity | 34/54 (63) | 30/50 (60) | 4/4 (100) | 0.285 |
Type 2 diabetes | 14/68 (21) | 12/64 (19) | 2/4 (50) | 0.185 |
Hypertension | 31/68 (46) | 27/64 (42) | 4/4 (100) | 0.039 |
Smoking history | 18/67 (27) | 16/63 (25) | 2/4 (50) | 0.291 |
Respiratory disease | 9/68 (13) | 9/64 (14) | 0/4 (0) | 1.0 |
Cardiovascular Disease | 14/68 (21) | 13/64 (20) | 1/4 (25) | 1.0 |
CT disease extent⁎ | ||||
Absent | 3/70 (4) | 3/66 (5) | 0/4 (0) | |
Mild | 36/70 (51) | 35/66 (53) | 1/4 (25) | |
Moderate | 22/70 (31) | 20/66 (30) | 2/4 (50) | |
Severe | 5/70 (7) | 5/66 (8) | 0/4 (0) | |
Critical | 4/70 (6) | 3/66 (5) | 1/4 (25) | |
Disease severity | ||||
Oxygen therapy | 38/68 (56) | 34/64 (53) | 4/4 (100) | 0.124 |
ICU | 16/70 (23) | 13/66 (20) | 3/4 (75) | 0.035 |
Mechanical ventilation | 12/70 (17) | 10/66 (15) | 2/4 (50) | 0.133 |
Death | 1/68 (1) | 1/64 (2) | 0/4 (0) | 1.0 |
Laboratory analysis | ||||
D dimer (μg/L) | 1694 ± 2890 [270–20,000] | 1102 ± 538 [270–2210] | 9394 ± 7024 [988–20,000] | 0.133 |
D dimer >5000 μg/L | 3/56 (5) | 0/52 (0) | 3/4 (75) | <0.001 |
CRP (mg/L) | 84 ± 72 [0–315] | 77 ± 62 [0–263] | 198 ± 118 [53–315] | 0.176 |
CRP > 25 mg/L | 55/69 (80) | 51/65 (78) | 4/4 (100) | 0.575 |
LDH (UI/L) | 413 ± 163 [197–1181] | 407 ± 166 [197–1181] | 488 ± 90 [355–608] | 0.226 |
LDH > 250 UI/L | 48/54 (89) | 44/50 (88) | 4/4 (100) | 1.0 |
Lymphopenia | 43/69 (62) | 40/65 (62) | 3/4 (75) | 1.0 |
Cochran-Armitage trend test.