Table 3.
Sensitivity (S), specificity (E), negative and positive predictive values (NPV and PPV) of the lowest and the highest risk strata of different prognostic indices in a cohort of nursing home residents with COVID-19 in Seville, Spain.
| Index and risk strata | Sensitivity | Specificity | NPV | PPV |
|---|---|---|---|---|
| PROFUND 0−2 points | 97 % (89−99%) | 12 % (8.2−17%) | 93 % (77−98%) | 24 % (19−30%) |
| PROFUND ≥11 points | 52 % (39−64%) | 74 % (68−79%) | 84 % (78−89%) | 36 % (27−47%) |
| CURB-65 0−1 points | 88 % (78−94%) | 67 % (60−73%) | 95 % (90−98%) | 43 % (35−52%) |
| CURB-65 ≥ 4 points | 23 % (14−35%) | 98 % (94−99%) | 82 % (76−86%) | 74 % (51−88%) |
| Charlson 0 points | 77 % (65−86%) | 23 % (18−29%) | 77 % (66−86%) | 22 % (17−28.5%) |
| Charlson ≥5 points | 15 % (8−26%) | 86 % (80−90%) | 78 % (72−83%) | 23 % (13−38%) |
| AA Charlson 0−3 points* | 94 % (86−98%) | 8% (5−12%) | 85 % (64−94%) | 23 % (18−28%) |
| AA Charlson ≥5 points | 80 % (69−88%) | 26 % (20−32%) | 82 % (71−89%) | 24 % (18−30%) |
| ACP 0−1 points# | 96 % (90−99%) | 1% (0.1−3%) | 50 % (9−90%) | 25 % (22−34%) |
| ACP = 3 points | 92 % (82−96%) | 29 % (23−35%) | 92 % (83−97%) | 27 % (21−33%) |
| Shi et al.& ≥2 | 79 % (67−87%) | 23 % (17−29%) | 79 % (67−87%) | 23 % (17−29%) |
| Shi et al. = 3 | 29 % (19−42%) | 83 % (77−87%) | 80 % (74−85%) | 33 % (22−47%) |
| PROFUND 0−2 points and CURB-65 0−1 points | 100 % (94−100%) | 8.5 % (5.5−13%) | 100 % (82−100%) | 24 % (19−29%) |
| PROFUND ≥11 points and CURB-65 ≥ 4 points | 13 % (7−24%) | 99 % (97−99.7%) | 80 % (74−84%) | 80 % (50−94%) |
AA: Adjusted by age; *There were no patients with a score ranging of 0−1 points and only 5 patients with 2 points; #There was only one patient with 0 points in the score; &There were no patients with 0 points in the score.