Table 3.
WBC, neutrophil, lymphocyte, and eosinophil counts (median and IQR) for infested and uninfested (control) SW, B6, and BALB/c mice at 14, 28, 56 and 112 d after Demodex infestation (dpi; n = 5 mice/group/strain/time point)
| WBC (× 103/µL) | Neutrophils (× 103/µL) | Lymphocytes (× 103/µL) | Eosinophils (× 103/µL) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Control | IQR | Infested | IQR | Control | IQR | Infested | IQR | Control | IQR | Infested | IQR | Control | IQR | Infested | IQR | |
| SW 14 dpi | 4.37 | 0.08 | 8.16 | 4.77 | 0.49 | 0.27 | 0.83 | 0.28 | 3.76 | 0.39 | 6.25 | 3.10 | 0.05 | 0.01 | 0.13 | 0.04 |
| SW 28 dpi | 7.63 | 0.16 | 12.65 | 2.38 | 0.87 | 0.25 | 1.26 | 0.45 | 6.41 | 0.22 | 11.09b,c | 1.73 | 0.03 | 0.03 | 0.27a | 0.20 |
| SW 56 dpi | 8.53 | 2.20 | 10.25 | 4.17 | 1.01 | 0.25 | 0.86 | 0.15 | 7.04 | 1.78 | 6.61 | 2.29 | 0.10 | 0.03 | 0.14 | 0.06 |
| SW 112 dpi | 7.61 | 1.48 | 8.65 | 3.42 | 1.04 | 0.41 | 1.15 | 0.01 | 6.11 | 1.55 | 7.11 | 3.57 | 0.10 | 0.14 | 0.16 | 0.02 |
| B6 14 dpi | 6.68 | 1.73 | 6.66 | 1.76 | 0.60 | 0.17 | 0.87 | 0.67 | 4.90 | 2.54 | 5.02 | 1.56 | 0.13 | 0.01 | 0.10 | 0.06 |
| B6 28 dpi | 9.65 | 4.93 | 5.95b,d | 1.42 | 3.54 | 4.28 | 1.36 | 0.74 | 6.94 | 0.81 | 4.69a | 1.25 | 0.27 | 0.08 | 0.15 | 0.04 |
| B6 56 dpi | 10.29 | 0.13 | 9.33 | 0.19 | 0.92 | 0.34 | 1.34 | 1.95 | 8.43 | 0.55 | 5.84 | 0.58 | 0.22 | 0.06 | 0.19 | 0.06 |
| B6 112 dpi | 8.57 | 1.85 | 7.88 | 2.07 | 1.00 | 0.14 | 0.81 | 0.32 | 7.06 | 2.27 | 6.45 | 2.23 | 0.11 | 0.09 | 0.17 | 0.09 |
| BALB/c 14 dpi | 11.14 | 0.57 | 9.25 | 3.91 | 2.50 | 1.36 | 2.11 | 2.15 | 7.36 | 1.21 | 6.64 | 0.60 | 0.23 | 0.05 | 0.19 | 0.06 |
| BALB/c 28 dpi | 11.46 | 2.26 | 12.36 | 1.40 | 1.43 | 0.08 | 1.75 | 0.43 | 9.45 | 1.67 | 9.53 | 0.72 | 0.22 | 0.03 | 0.24 | 0.05 |
| BALB/c 56 dpi | 9.12 | 1.14 | 9.80 | 0.64 | 1.14 | 0.69 | 1.67 | 0.14 | 7.38 | 0.48 | 7.57 | 1.41 | 0.18 | 0.08 | 0.31 | 0.10 |
| BALB/c 112 dpi | 9.25 | 1.93 | 9.59 | 0.80 | 1.22 | 0.42 | 1.50b | 0.21 | 8.02 | 1.38 | 7.15 | 1.18 | 0.11 | 0.04 | 0.12 | 0.02 |
The dpi at which the cell population was significantly (aP ≤ 0.05; bP ≤ 0.01) different between infested and uninfested (control) animals is shown. In addition, select values were outside of the published reference range. Monocyte populations were also evaluated; there were no significant differences between control and infested animals of any strain at any time point.
Above upper limit of reference range (Charles River Laboratories, Clinical Pathology Data for North American CFW Mouse Colonies)
Below lower limit of reference range (Charles River Laboratories, Clinical Pathology Data for North American C57BL/6NCrl Mouse Colonies)