Table 3.

Univariate and multivariate analysis of associations between clinical characteristics at first hemodialysis session following COVID-19 infection and risk of hospital admission or death by 28 days

Outcome	Characteristic	Univariate analyses		Multivariate analyses
		Odds ratio (95% confidence interval)	P value	Odds ratio (95% confidence interval)	P value
Hospital admission	Active transplant waiting list status	0.3 (0.13–0.85)	0.02	0.18 (0.03–0.83)	0.04
	Uses institutional transport	3.3 (1.41–7.57)	0.005	4.35 (1.17–18.58)	0.03
	Autoimmune cause ESKD	0.2 (0.06–0.73)	0.02		NS
	Diabetes as cause ESKD	2.5 (1.13–5.29)	0.03		NS
	Breathlessness at HD1	3.3 (1.41–8.33)	0.01		NS
		Difference between medians (95% confidence interval)	P value
	Predialysis SaO2	1% (0.01–2)	0.03		NS
	Increased white cell count	1.0 x 109/l (0.2–1.7)	0.02	1.45 (1.06–2.13)	0.03
	Increased CRP	65 mg/l (15–79)	0.0001		NS
	Increased LDH	73 unit/l (13–93)	0.008		NS
	Increased ferritin	170 μg/l (36–474)	0.02		NS
	Increased troponin	26 ng/l (3–33)	0.02		NS
	Increased D-dimer	925 μg/l (345–1351)	0.0005		NS
Death by 28 days	Age	11.5 years (3–17)	0.008	1.10 (1.03–1.19)	0.01
		Odds ratio (95% confidence interval)	P value
	Diabetes as cause ESKD	4.3 (1.46–11.6)	0.01		NS
	Diarrhea at HD1	0.1 (0.001–0.75)	0.04		NS
		Difference between medians (95% confidence interval)	P value
	Increased white cell count	1.1 x 109/l (0.3–2.9)	0.02		NS
	Increased CRP	103 mg/l (20–121)	0.001		NS
	Increased LDH	72 unit/l (12–122)	0.02		NS
	Increased troponin	30 ng/l (9–93)	0.006		NS

COVID-19, coronavirus disease 2019; CRP, C-reactive protein; ESKD, end-stage kidney disease; HD1, first hemodialysis session following COVID-19 diagnosis; LDH, serum lactate dehydrogenase; NS, nonsignificant; SaO₂, peripheral oxygen saturations.

The multivariate analyses included all features demonstrating significant associations at univariate analysis.