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. 2020 Aug 24;22(8):e22033. doi: 10.2196/22033

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©Michael P McRae, Isaac P Dapkins, Iman Sharif, Judd Anderman, David Fenyo, Odai Sinokrot, Stella K Kang, Nicolaos J Christodoulides, Deniz Vurmaz, Glennon W Simmons, Timothy M. Alcorn, Marco J Daoura, Stu Gisburne, David Zar, John T McDevitt. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 24.08.2020.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on http://www.jmir.org/, as well as this copyright and license information must be included.

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Spaghetti plot of longitudinal COVID-19 Biomarker Scores for patients in the external validation set from Tongji Hospital [21] between January 10 and February 18, 2020. These data represent individual patients’ scores over a median (IQR) of 12.5 (8–17.5) days between admission and outcomes of discharged or deceased. The first scores available after admission were significantly higher in those that died vs those that were discharged (AUC 0.97, cutoff score of 19), and over time patients who were discharged had an average decrease in score (-4.7) while those that died had an average increase in score (+11.2).