Table 2.

Internal validation performance in terms of AUC, sensitivity, specificity, PPV, and NPV (95% CI) from 5-fold cross-validation. The Tier 1 and 2 models were trained and tested using data from Family Health Centers at New York University.

	Tier 1 Outpatient Model	Tier 2 Biomarker Model
AUCa	0.79 (0.74-0.84)	0.95 (0.92-0.98)
Sensitivity	0.73 (0.69-0.76)	0.89 (0.86-0.92)
Specificity	0.73 (0.69-0.76)	0.89 (0.86-0.92)
PPVb	0.34 (0.30-0.38)	0.70 (0.65-0.74)
NPVc	0.93 (0.91-0.95)	0.97 (0.94-0.98)

^aAUC: area under the curve.

^bPPV: positive predictive value.

^cNPV: negative predictive value.