Fig. 3. Stability analysis of p19INK4d analogues using CD. (A) Single measurement of thermal scans from 10 °C to 70 °C obtained for all the analogues of p19INK4d at 222 nm and 208 nm wavelength. (B) Folded fraction plotted against temperature calculated using the Boltzmann equation to fit the sigmoidal curves obtained from thermal scans at 222 nm in Fig. 3A. (C) Mean Tm values ± SD °C of the four analogues acquired from three independent measurements for each analogue (ESI, Fig. S21†).
