Table 2. Minimal inhibitory concentration results of the eight non-repetitive B. pseudomallei isolates.
Antimicrobial susceptibility results (μg/mL) | Breakpoints | MIC of the eight isolates | Range | |||||||
---|---|---|---|---|---|---|---|---|---|---|
Isolate 1 | Isolate 2 | Isolate 3 | Isolate 4 | Isolate 5 | Isolate 6 | Isolate 7 | Isolate 8 | |||
Imipenem | S≦4, R≧16 | 0.50 | 0.75 | 0.75 | 0.75 | 0.25 | 0.5 | 0.5 | 0.38 | 0.25~0.75 |
Ceftazidime | S≦8, R≧32 | 2 | 4 | 2 | 4 | 1 | 3 | 2 | 2 | 1~4 |
Amoxicillin/clavulanate | S≦8/4, R≧32/16 | 2/1 | 4/2 | 8/4 | 12/6I | 2/1 | 8/4 | 8/4 | 8/4 | 2/1~12/6 |
Doxycycline | S≦4, R≧16 | 2 | 2 | 6 | >256R | 2 | 3 | 12 | 3 | 2~125 |
TMP-SMZ | S≦2/38, R≧4/76 | 0.25/4.75 | 2/38 | 4/76 | 2/38 | 0.5/9.5 | 2/38 | 2/38 | 2/38 | 0.25/4.75~4/76 |
Notes: MIC, minimum inhibitory concentration; S, susceptible; I, intermediate; R, resistant; MIC range, range of minimum inhibitory concentration; TMP-SMZ: Trimethoprim/sulfamethoxazole